Posts

A novel role for the SUMO E3 ligase PIAS1 in cancer metastasis

Simalikalactone E (SkE), a new weapon in the armamentarium of drugs targeting cancers that exhibit constitutive activation of the ERK pathway

Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide

Targeting JNK-interacting-protein-1 (JIP1) sensitises osteosarcoma to doxorubicin

High cytidine deaminase expression in the liver provides sanctuary for cancer cells from decitabine treatment effects

The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis.

Effects of Ectopic Expression of NGAL on Doxorubicin Sensitivity

Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma

Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma

The central role of chromatin maintenance in aging